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Thyroid storm overview

Thyroid Storm Overview

The thyroid gland, located at the front part of the neck, is responsible for making thyroid hormone that is important for all body cells to work properly.

In certain conditions, the thyroid becomes over-active and produces too much of its hormone, a situation called hyperthyroidism. People with hyperthyroidism have problems that reflect over-activity of the organs of the body, resulting in symptoms such as sweating, feeling hot, rapid heartbeats, weight loss, and sometimes eye problems. When the levels of thyroid hormones become very high in a patient who has hyperthyroidism, the symptoms get worse and can result in a serious condition called thyroid storm. One major sign of thyroid storm that differentiates it from plain hyperthyroidism is a marked elevation of body temperature. Thyroid storm is unusual, but when it occurs, it is a life-threatening emergency. People experiencing symptoms of thyroid storm should be taken to a hospital's accident and emergency department.

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Thyroid storm triggers

  • Infections
  • Injury or trauma
  • Recent thyroid surgery
  • Stopping medications given for hyperthyroidism
  • Too high a dose of thyroid hormone
  • Treatment with radioactive iodine
  • Pregnancy
  • Heart attack or heart emergencies

Thyroid storm symptoms

  • Rapid heart beats
  • Greatly increased body temperature
  • Chest pain
  • Shortness of breath
  • Anxiety and irritability
  • Disorientation
  • Increased sweating
  • Weakness
  • Heart failure

When to seek medical advice

If you have any of the following conditions, then seek medical advice immediately:

  • Fever
  • Very rapid heart beats
  • Confusion and disorientation
  • Significant fatigue and exhaustion

Friends or family members of anyone experiencing symptoms of thyroid storm who may not be able to function normally should take the individual to an A&E department immediately.

Examinations and tests

The following tests are usually performed: blood tests to check blood cell count, electrolyte levels, sugar level, and thyroid hormone levels. Liver function tests are also usually performed.

Thyroid storm treatment - self-care at home

People experiencing thyroid storm are not able to function normally. This is a life-threatening emergency. People experiencing symptoms of thyroid storm should be taken to the A&E department.

Medical treatment

  • A complete evaluation to determine the cause of thyroid storm
  • Intravenous fluids and electrolytes
  • Oxygen if needed 
  • Fever control with antipyretics (fever-reducing medication) and if needed cooling blankets
  • Intravenous corticosteroids such as hydrocortisone
  • Medication to block the production of thyroid hormones 
  • Iodide to block thyroid hormone release
  • Block the action of thyroid hormones on the cells by drugs called beta-blockers
  • Treatment of heart failure if present

Next steps

  • Following the start of treatment, careful monitoring, usually in the intensive care unit, is necessary.
  • Following recovery from thyroid storm, options for definitive treatment are radioactive iodine or antithyroid medications; surgery is rarely needed.

Follow-up

Follow-up with the doctor after discharge is important to monitor the thyroid condition and formulate a plan for curative treatment.

Prevention

Thyroid storm can be prevented with early treatment of hyperthyroidism and recognition of the warning symptoms of thyroid storm.

Outlook

  • Thyroid storm is a very serious condition that can result in death.
  • Early and aggressive treatment can improve the outcome.

WebMD Medical Reference

Medically Reviewed by Dr Rob Hicks on November 07, 2011

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