Forgetting where you put your keys, forgetting words or names, and taking longer to learn new things are indications of mild forgetfulness, which is common as we age. However, getting lost in places you know well can signal a more serious problem such as Alzheimer's disease, depression, or a blood clot. Other signs of a serious memory problem include asking the same questions repeatedly, not being able to follow directions, becoming confused about time, people, and places, and forgetting to take proper care of yourself.