Precancerous skin lesions and skin cancer slideshow
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The warning signs of skin cancer
Like many cancers, skin cancers – including melanoma, basal cell carcinoma and squamous cell carcinoma – start as precancerous lesions. These precancerous lesions are changes in skin that are not cancer but could become cancer over time. The NHS says skin cancer affects more than 100,000 people in the UK each year. Learn to spot the early warning signs. Skin cancer can be cured if it's found and treated early.
Actinic keratosis (solar keratosis)
The small, scaly patches caused by too much sun exposure commonly occur on the head, neck, or hands, but can be found elsewhere. They're the early beginnings of skin cancer. Actinic keratosis usually appears on people after the age of 40, but they can show up in much younger people. Fair-skinned, blonde or red-haired people with blue or green eyes are most at risk. They can develop into squamous cell skin cancer. Most do not become cancerous but doctors recommend treatment to prevent them developing into squamous cell skin cancer.
Actinic cheilitis
Related to actinic keratosis, actinic cheilitis is a precancerous condition that usually appears on the lower lips. Scaly patches or persistent roughness and cracking of the lips may be present. Less common symptoms include swelling of the lip, loss of the sharp border between the lip and skin, and prominent lip lines. Actinic cheilitis may evolve into invasive squamous cell carcinoma if not treated.
Cutaneous horns
The cutaneous horn appears as a funnel-shaped growth that extends from a red base on the skin. It is composed of compacted keratin (the same protein in nails). It is a type of actininc keratosis. The size and shape of the growth can vary considerably, but most are a few millimetres in length. Squamous cell carcinoma can be found at the base. It usually occurs in fair-skinned elderly adults with a history of significant sun exposure.
When is a mole a problem?
A mole (naevus) is a benign growth of melanocyte skin cells, which give skin its colour. While very few moles become cancer, abnormal or atypical moles can develop into melanoma over time. 'Normal' moles can appear flat or raised or may begin flat and become raised over time. The surface is typically smooth. Normal moles are usually round or oval and no larger than 6mm diameter. Most moles develop in youth or young adulthood. It's unusual to acquire a mole in middle age and beyond.
Dysplastic naevi (atypical moles)
Atypical moles are not cancer, but they can become cancer. They can be found in sun-exposed or sun-protected areas of the body. Atypical moles may be larger (6mm or a quarter of an inch across or larger) or more irregular in shape, with notched or fading borders. They may be flat or raised or the surface smooth or rough. They are typically of mixed colour, including pink, red, tan and brown.
Know your ABCD
Most moles on a person's body look similar to one another. A mole or freckle that looks different from the others or that has a diameter larger than 6mm or any characteristics of the ABCD of melanoma should be checked by a doctor. It could be cancerous. The ABCD highlights important characteristics to consider when examining your moles or other skin growths. You can learn about them in the slides to come.
Know your ABCD: 'A' is for asymmetry
Asymmetry means one half of a mole does not match the other half. Normal moles are symmetrical. When checking your moles or freckles, draw an imaginary line through the middle and compare the two halves. If they do not look the same on both sides, ask your doctor to check it.
Get moles checked if they change or look suspicious
A mole that is evolving – shrinking, growing larger, changing colour, begins to itch or bleed – should be checked If a portion of the mole appears elevated or raised from the skin, ask your doctor to check it. Melanoma lesions often grow in size or change in height rapidly.
Tips for screening moles for cancer
Examine your skin regularly. A common location for melanoma in men is on the back, and in women, the lower leg. But check your entire body for moles or suspicious spots. The NHS suggests doing this once every couple of months. Start at your head and work your way down. Check the 'hidden' areas: between fingers and toes, the groins, soles of the feet, the backs of the knees. Check your scalp, ears and neck for moles. Use a handheld mirror or ask a family member to help you look at these areas. You should be especially suspicious of a new mole. Take a photo of moles and date it to help you monitor them for change. Pay special attention to moles if you're a teenager, pregnant or going through the menopause – times when your hormones may be surging.
How are moles evaluated?
If you find a mole or spot that has any ABCD signs of possible melanoma – or one that's tender, itching, oozing, scaly, doesn't heal or has redness or swelling beyond the mole – seek medical advice. Your doctor may want to have the mole biopsied. If found to be cancerous, the entire mole and a rim of normal skin round it will be removed and the wound closed with stitches. Additional treatment may be needed
An introduction to skin cancer
Malignant melanoma, especially in the later stages, is serious and treatment is difficult. Early diagnosis and treatment can increase the survival rate. Nonmelanoma skin cancers include basal cell carcinoma and squamous cell carcinoma. Both are common and are almost always cured when found early and treated. People who've had skin cancer once are at risk of getting it again; they should have regular checkups as advised by their specialist.
Squamous cell carcinoma
This nonmelanoma skin cancer may appear as a firm red nodule, a scaly growth that bleeds or develops a crust, or a sore that doesn't heal. It most often occurs on the nose, forehead, ears, lower lip, hands and other areas of the body exposed to the sun. Squamous cell carcinoma is curable if caught and treated early. If the skin cancer becomes more advanced, treatment will depend on the stage of cancer.
Bowen's disease
Bowen's disease is also called squamous cell carcinoma 'in situ.' It is a type of skin cancer that spreads outwards on the surface of the skin. By contrast, 'invasive' squamous cell carcinomas can grow inwards and spread to the interior of the body. Bowen's disease looks like scaly, reddish patches that may be crusted; it may be mistaken for rashes, eczema, fungus or psoriasis.
Basal cell carcinoma
Basal cell carcinoma is the most common and easiest to treat skin cancer. Because basal cell carcinoma spreads slowly, it occurs mostly in adults. Basal cell tumours can take on many forms, including a pearly white or waxy bump, often with visible blood vessels, on the ears, neck or face. Tumours can also appear as a flat, scaly, flesh-coloured or brown patch on the back or chest, or more rarely, a white, waxy scar.
Less common skin cancers
Uncommon types of skin cancer include Kaposi's sarcoma, mainly seen in people with weakened immune systems; sebaceous gland carcinoma, an aggressive cancer originating in the oil glands in the skin; Merkel cell carcinoma, which is usually found on sun-exposed areas on the head, neck, arms or legs but often spreads to other parts of the body.
Who gets skin cancer, and why?
Sun exposure is the biggest cause of skin cancer. But it doesn't explain skin cancers that develop on skin that isn't usually exposed to sunlight. Exposure to environmental hazards, radiation treatment and even heredity may play a role. Although anyone can get skin cancer, the risk is greatest for people who have:
- Fair skin or light-coloured eyes
- An abundance of large and irregularly-shaped moles
- A family history of skin cancer
- A history of excessive sun exposure or blistering sunburns
- Lived at high altitudes or with year-round sunshine
- Received radiotherapy treatments
Reduce your risk of skin cancer
Limit your exposure to the sun's ultraviolet rays, especially between 11 am and 3 pm, when the sun's rays are strongest. Apply sunscreen liberally before going outside (don't forget the lips and ears!), wear a hat and sunglasses and cover up with clothing. And remember, if you notice changes to your skin such as a new growth, a mole changing appearance, or a sore that won't heal, seek medical advice promptly.
Related Reading
Medically Reviewed by Dr Rob Hicks on June 29, 2012
IMAGES PROVIDED BY:
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(10) © 2007 Interactive Medical Media LLC. All rights reserved.
(11) "Fitzpatrick's Color Atlas & Synopsis of Clinical Dermatology"; Klaus Wolff, Richard Allen Johnson, Dick Suurmond; Copyright 2005, 2001, 1997, 1993 by The McGraw-Hill Companies. All Rights reserved.
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(13) Robert Decelis Ltd / Photographer's Choice / Getty Images
(14) Phanie / Photo Researchers, Inc.
(15) Biophoto Associates / Photo Researchers, Inc.
(16) Top left and right, and bottom left and right images from "Fitzpatrick's Color Atlas & Synopsis of Clinical Dermatology"; Klaus Wolff, Richard Allen Johnson, Dick Suurmond; Copyright 2005, 2001, 1997, 1993 by The McGraw-Hill Companies. All Rights reserved. Bottom center image from Dr. Kenneth Greer, Visuals Unlimited, Getty Images.
(17) © 2007 Interactive Medical Media LLC. All rights reserved.
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(19) Top and bottom left from "Fitzpatrick's Color Atlas & Synopsis of Clinical Dermatology"; Klaus Wolff, Richard Allen Johnson, Dick Suurmond; Copyright 2005, 2001, 1997, 1993 by The McGraw-Hill Companies. All Rights reserved. Top right: © 2007 Interactive Medical Media LLC. All rights reserved. Bottom left: Copyright © ISM / Phototake -- All rights reserved.
(20) Left side and bottom right from "Fitzpatrick's Color Atlas & Synopsis of Clinical Dermatology"; Klaus Wolff, Richard Allen Johnson, Dick Suurmond; Copyright 2005, 2001, 1997, 1993 by The McGraw-Hill Companies. All Rights reserved. Top right: © 2007 Interactive Medical Media LLC. All rights reserved.
(21) Nacivet / Taxi / Getty Images
(22) Mike Powell / Taxi / Getty Images
References:
NHS Choices: "Moles."
American Academy of Dermatology: "Actinic keratoses," "Moles," "Skin Cancer."
American Academy of Family Physicians: "Skin Cancer: Reduce Your Risk With 'Safe-Sun' Guidelines."
American Cancer Society: "Kaposi Sarcoma," "Melanoma Skin Cancer," "Skin Cancer Facts."
American Melanoma Foundation: "ABCD's of Melanoma."
American Osteopathic College of Dermatology: "Bowen's Disease."
Medscape Reference: "Cutaneous Horn," "Sebaceous Gland Carcinoma."
Melanoma Research Foundation: "ABCDEs of Melanoma," "What Is Melanoma?"
National Cancer Institute, National Institutes of Health: "General Information About Merkel Cell Carcinoma," "Sun Protection."
New Zealand Dermatological Society, Inc.'s DermNet: "Solar cheilitis."
Skin Cancer Foundation: "Basal Cell Carcinoma."
This tool does not provide medical advice. See additional information:
THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. It is intended for general information purposes only and does not address individual circumstances. It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. Never ignore professional medical advice in seeking treatment because of something you have read on the Boots WebMD Site. If you have an urgent medical problem please call your general practitioner, NHS Direct, or NHS 24 immediately or in the case of emergencies dial 999.
© 2012 WebMD, LLC. All rights reserved.
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