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This article is from the WebMD News Archive
New MS test comes to the UK
8th April 2010 -- Chronic cerebrospinal venous insufficiency (CCSVI) is a
hot topic for people with MS at the moment. The new theory is that multiple
sclerosis can be caused by blockages in veins draining blood from the brain:
Clear the blockages - and MS symptoms may be reduced.
The idea was put forward by an Italian scientist, Dr Paolo Zamboni.
Up until now anyone from the UK wanting to be tested or treated for the
condition has had to travel to clinics in Italy or Poland.
Now a Glasgow clinic has started to take bookings for diagnostic tests this
summer and plans to offer treatment to patients who are found to have
CCSVI.
About MS
Multiple sclerosis is the most common neurological condition among young adults in the UK, affecting approximately 85,000 people.
CCSVI: The theory
Zamboni investigated links between MS and iron deposits in blood
vessels.
He used ultrasound on the blood vessels leading in and out of the brain and
found that in a majority of people with MS, including his wife, the veins
taking blood away from the brain were blocked or damaged. This was not the case
in people without MS.
He further suggested that iron was damaging the blood vessels and allowing the
heavy metal, along with other unwelcome cells, to cross the crucial blood-brain
barrier, a process he termed Chronic Cerebrospinal Venous Insufficiency.
Putting CCSVI to the test
MS is a condition which has attracted more than its fair share of miracle
cures and scams. However supporters of the blocked vein theory remain
optimistic after the first randomised clinical study in the US.
More than 55% of 500 MS patients participating in the initial phase of a study
at the University of Buffalo exhibited narrowing of the extracranial veins,
causing restriction of normal outflow of blood from the brain.
The study findings will be presented to the American Academy of Neurology
meeting later this month.
Testing comes to the UK
The Essential Health Clinic in Glasgow has a large private practice for MS.
Dr Tom Gilhooly sees patients from all over the UK and abroad for treatments
like low dose naltrexone (LDN).
At first he thought the CCSVI concept was “whacky” but his patients kept asking
about it. He read the scientific papers about it and tells us “I thought there
is a biological plausibility here. You could see why venous drainage could
impact on the immune system and therefore on the central nervous system and
MS.”
The new approach, he says, is “potentially revolutionary”.
Gilhooly then set about planning for a screening service with a vascular
stenographer and is setting up training for his staff at Zamboni’s clinic and
at a centre in Poland.
Demand is such that he’s also expanding to set up a London clinic to offer the
service.
“Interest has been intense. We’ve almost been blown away by it. The
organisation has struggled to cope with the number of phone calls”.
More than 2,000 people have registered an interest in the screening at his
clinic.

