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DTaP/IPV/Hib, DTaP/IPV and Td/IPV vaccines

DTaP/IPV/Hib 5-in-1 vaccine

DTaP/IPV/Hib is the 5-in-1 vaccine the NHS offers to all babies to help give immunity to five potentially life-threatening diseases:

Diphtheria - a respiratory disease that can cause breathing problems, paralysis, heart failure and death. It is spread by coughs and sneezes and is very contagious.

Tetanus (lockjaw) - caused by bacteria often found in the soil. Once it enters the body it releases toxins that attack the nervous system, causing muscle spasms and death if left untreated.

Whooping cough (pertussis) - a highly contagious infection causing coughing spasms that make it hard for the child to eat, drink or breathe. It can lead to pneumonia, seizures, brain damage and death.

Polio - a mild condition in most cases, but it can cause paralysis and death. It causes very few symptoms and some people do not notice any symptoms. A mild case of polio usually causes flu-like symptoms, which may include sore throat, a fever of 38C or higher, nausea, vomiting, diarrhoea and constipation.

Haemophilus influenzae type b (Hib) - a type of infection that can cause a number of other illnesses, such as blood poisoning, meningitis and pneumonia.

How is the 5-in-1 vaccination given?

This 5-in-1 vaccine is given in three doses to gradually increase immunity at 8, 12 and 16 weeks of age.

The injection goes into the thigh.

To reduce the number of visits to the doctor or clinic, the 5-in-1 jabs may be given at the same time as other vaccinations, including rotavirus, pneumococcal and Men B (meningitis B) vaccines.

Most babies can have the 5-in-1 jabs, but they may not be recommended for babies who:

  • Are allergic to the vaccine
  • Have a fever on the appointment day - colds and coughs are usually fine
  • Have some neurological problems or epilepsy that is not well controlled.

Sticking to the childhood immunisation timetable is best to protect a growing baby, but if a child misses one of the 5-in-1 vaccinations, boosters can be given later.

Is the 5-in-1 vaccine safe?

The NHS says the vaccinations are very safe, and there's no chance of babies getting the diseases the jabs protect against because they don’t contain any 'live' organisms.

Common side-effects for around 1 in 10 babies include:

  • Being irritable or crying more after the injection
  • A small bump, redness and swelling at the injection site for a time afterwards
  • Fever
  • Vomiting
  • Lost appetite.

Rare side effects for 1 in 10,000 babies include:

  • Fever over 39.5C
  • Seizures.

Very rare side effect in 1 in 100,000 cases:

Seek medical advice if you have concerns about your baby's health after a vaccination.

Age-appropriate paracetamol may help with mild fever. Cool drinks and reducing clothing layers or blankets can also help.

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